LECTURES

Modern glycobiology with DNA scissors

The third language of life after the genome and the protein is considered to be the Glycomet. The glyphs of a cell are complex carbohydrates on proteins and lipids, and more than 2% of the cells ' genes are used for synthesis and degradation of the glycomet. The carbohydrates are found as long branched chains with very large structural variation, and the individual Carboassay structures have very specific roles for virtually all biological conditions in a cell and organism. Today, for example, is known as Over 100 diseases caused by a lack of carboenzyme enzymes. Technical barriers have long hampered analysis of specific functions of carbohydrates, but with new genetic engineering techniques (ZFN, TALENs, CRISPR/Cas9) We can change carbohydrate chains as in a building set of Lego bricks. A small revolution that makes the dissectioning of functions and mechanisms possible.

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Modern glycobiology with DNA scissors

Date: 16. Nov 2015
Time: 19:30:00

Lecturer: Professor Henrik Clausen
Institution: CCG, University of Copenhagen
Address:

The Lecture is held: Geologisk Museum Øster voldgade 5-7, 1350 Copenhagen

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